Polymorph screening

Polymorph screening is the identification and characterisation of all relevant polymorphic forms of a pharmaceutical compound.  Many pharmaceutical compounds are able to form two or more crystalline phases, this is known as polymorphism. It is important that the polymorphs of a compound are assessed, as different polymorphs have different physicochemical properties that may have an impact on the intended use of the material. The selection of a specific crystal form of an API early in drug discovery mitigate the chances of risk in the later stages of development.

  • Reduced risk of failure during development
  • Meeting regulatory requirements
  • Strengthened intellectual property
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Liz Edmond

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