Asymmetric transfer hydrogenation kit
Johnson Matthey’s isometric transfer hydrogenation catalysts are the technology of choice for the reduction of C=O and C=C double bonds to manufacture chiral alcohols and chiral amines. The catalysts in the kit demonstrates excellence tolerance to a wide variety of functional groups including NO2, CN, COOR, CONR2, OH, and NH2. They are effective across both acidic and basic conditions.
The chiral catalysts are typically highly chemoselective, reducing C=O groups without affecting C=C bond. These systems are also effective for imine reductions and reductive aminations, provided that suitable reactions conditions are chosen.
R-enantiomers kit contents
| Product number | Product description | CAS number | Mol weight |
|---|---|---|---|
| C1-000 | [(R,R)-TsDPEN Ru(p-cymene)Cl] | 14647-23-5 | 636.2 |
| C1-001 | [(R,R)-MsDPEN Ru(p-cymene)Cl] | 1097730-63-6 | 560.11 |
| C1-008 | [(R,R)-FsDPEN Ru(p-cymene)Cl] | 1026995-71-0 | 712.13 |
| C1-017 | [(1R,4S)(1R,2R)-CsDPEN Ru (p-cymene)Cl] | N/A | 696.31 |
| C1-020 | [(R,R)-TsDPEN Ru(mesitylene)Cl] | 174813-82-2 | 622.18 |
| C1-100 | [(R,R)-TsDACH Ru(p-cymene)Cl] | 213603-12-4 | 538.11 |
| C1-300 | C3-[(R,R)-teth-TsDPEN RuCl] | 1192620-83-9 | 620.17 |
| C1-304 | C3-[(R,R)-teth-MtsDPEN RuCl] | 162123-45-0 | 648.22 |
| C1-308 | C3-[(R,R)-teth-TrisDPEN RuCl] | 1629123-54-1 | 732.38 |
| C1-358 | C4-[(R,R)-teth-TrisDPEN RuCl] | 1629123-68-7 | 746.40 |
| C3-020 | [(R,R)-TsDPEN IrCp*Cl] | 1244963-99-2 | 728.37 |
| C3-021 | [(R,R)-MsDPEN IrCp*Cl] | 2598217-78-6 | 652.27 |
| C3-022 | [(1R,4S)(1R,2R)-CsDPEN IrCp*Cl] | 895579-52-9 | 788.46 |
S-enantiomers kit contents
| Product number | Product description | CAS number | Mol weight |
|---|---|---|---|
| C1-007 | [(1S,4R)(1S,2S)-CsDPEN Ru (p-cymene)Cl] | 3067212-22-7 | 696.31 |
| C1-010 | [(S,S)-TsDPEN Ru(p-cymene)Cl] | 192139-90-5 | 636.2 |
| C1-011 | [(S,S)-MsDPEN Ru(p-cymene)Cl] | 329371-25-7 | 560.11 |
| C1-018 | [(S,S)-FsDPEN Ru(p-cymene)Cl] | 1026995-72-1 | 712.13 |
| C1-030 | [(S,S)-TsDPEN Ru(mesitylene)Cl] | 174813-81-1 | 622.18 |
| C1-110 | [(S,S)-TsDACH Ru(p-cymene)Cl] | 192057-12-8 | 538.11 |
| C1-310 | C3-[(S,S)-teth-TsDPEN RuCl] | 851051-43-9 | 620.17 |
| C1-314 | C3-[(S,S)-teth-MtsDPEN RuCl] | 1630734-19-8 | 648.22 |
| C1-318 | C3-[(S,S)-teth-TrisDPEN RuCl] | 1630734-20-1 | 732.38 |
| C1-319 | C3-[(R,R)-teth-TsDPEN RuCl] dimer | 851136-36-2 | 1386.18 |
| C1-368 | C4-[(S,S)-teth-TrisDPEN RuCl] | 1630736-02-5 | 746.40 |
| C3-030 | [(1R,4S)(1R,2R)-CsDPEN IrCp*Cl] | 1099830-90-6 | 728.37 |
| C3-031 | [(S,S)-MsDPEN IrCp*Cl] | 1085182-50-8 | 652.27 |
| C3-032 | [(1S,4R)(1S,2S)-CsDPEN IrCp*Cl] | 895579-53-0 | 788.46 |
