Hydrogenation of anilines catalysts
Aniline functional groups are commonly found in key starting materials and reaction intermediates used in the production of important small molecules. The hydrogenation of anilines are a widely applied transformation across the fine chemical, agrochemical, and pharmaceutical industry. The conversion of aromatic amines to their corresponding cyclohexylamine derivatives is a particularly important example of industrially relevant aniline hydrogenation.
Hydrogenation of anilines in complex molecules requires careful catalyst selection and optimisation of reaction conditions to achieve the desired transformation efficiently. Sovent, temperature, and H2 pressure choices are critical to achieve the required selectivity and activity, without the formation of unwanted byproducts.