Chiral ligands
Chiral phosphine ligands are a critical tool that enables transition metal catalysis to achieve highly chemo-, diastero- and enatioselective transformations. While preformed ligand-metal complexes may provide practical advantages and higher productivity, the use of chiral ligands with platinum group metal (PGM) or earth abundant metal (EAM) precursors have their own advantages. They allow for greater exploration of a vast chemical space and the rapid identification of suitable catalysts for the desired asymmetric transformation.
Advantages of chiral ligands:
- A critical enabling and tunable component for any asymmetric catalytic step.
- Broad scope for discovery of new transformations when combined with metal PGM and EAM precursors.
- Ideal to develop new applications and to find the best substrate-catalyst combinations.
Chiral phosphine ligand options
(R)-P-Phos
Product number: C4-000
CAS number: 221012-82-4
Mol weight: 644.64
Reaction type: asymmetric hydrogenation
(R)-Phanephos
Product number: C4-005
CAS number: 364732-88-7
Mol weight: 576.64
Reaction type: asymmetric hydrogenation
(R)-Xyl-Phanephos
Product number: C4-007
CAS number: 325168-89-6
Mol weight: 688.86
Reaction type: asymmetric hydrogenation
(S)-P-Phos
Product number: C4-020
CAS number: 362524-23-0
Mol weight: 644.64
Reaction type: asymmetric hydrogenation
(S)-Phanephos
Product number: C4-025
CAS number: 192463-40-4
Mol weight: 576.64
Reaction type: asymmetric hydrogenation
(S)-Xyl-Phanephos
Product number: C4-027
CAS number: 325168-88-5
Mol weight: 688.86
Reaction type: asymmetric hydrogenation
(R)-Me-Bophoz
Product number: C4-040
CAS number: 2841781-21-1
Mol weight: 611.47
Reaction type: asymmetric hydrogenation
(R)-H-[P(R)-H8-BINOL]-BoPhoz
Product number: C4-045
CAS number: 1914993-89-7
Mol weight: 735.61
Reaction type: asymmetric hydrogenation
(S)-Me-Bophoz
Product number: C4-060
CAS number: 905857-95-6
Mol weight: 611.47
Reaction type: asymmetric hydrogenation
(S)-H-[P(S)-H8-BINOL]-BoPhoz
Product number: C4-065
CAS number: 851761-23-4
Mol weight: 735.61
Reaction type: asymmetric hydrogenation
