Ruthenium Wills catalysts

Johnson Matthey’s portfolio of ruthenium Wills catalysts provides high conversion selectivity in transformations where ruthenium Noyori catalysts are less effective. They work under both transfer hydrogenation and hydrogenation conditions in the reduction of carbonyl and imine moieties. Very low and cost-effective catalyst loadings can be achieved on a vast number of poly-functionalised ketones and imines, including bulky ketones and acyclic imines. 

Advantages of ruthenium Wills catalysts:

  • Extremely robust and effective asymmetric transfer hydrogenation and hydrogenation catalysts.
  • High conversion and selectivity on complex substrates.
  • Very effective in direct reductive amination.
  • Effective in reductions with dynamic kinetic resolution.

Ruthenium Wills catalyst options

C3-[(R,R)-teth-TsDPEN-RuCl]
Product number: C1-300
CAS number: 1182620-83-9
Mol weight: 620.17
Reaction type: transfer hydrogenation, reductive amination, hydrogenation
C3-[(S,S)-teth-TsDPEN-RuCl]
Product number: C1-310
CAS number: 851051-43-9
Mol weight: 620.17
Reaction type: transfer hydrogenation, reductive amination, hydrogenation
C3-[(R,R)-teth-MtsDPEN RuCl]
Product number: C1-304
CAS number: 162123-45-0
Mol weight: 648.22
Reaction type: transfer hydrogenation, reductive amination, hydrogenation
C3-[(S,S)-teth-MtsDPEN RuCl]
Product number: C1-314
CAS number: 1630734-19-8
Mol weight: 648.22
Reaction type: transfer hydrogenation, reductive amination, hydrogenation
C3-[(R,R)-teth-TrisDPEN RuCl]
Product number: C1-308
CAS number: 1629123-54-1
Mol weight: 732.38
Reaction type: transfer hydrogenation, reductive amination, hydrogenation
C3-[(S,S)-teth-TrisDPEN RuCl]
Product number: C1-318
CAS number: 1630734-20-1
Mol weight: 732.38
Reaction type: transfer hydrogenation, reductive amination, hydrogenation
C4-[(R,R)-teth-TrisDPEN RuCl]
Product number: C1-358
CAS number: 1629123-68-7
Mol weight: 746.4
Reaction type: transfer hydrogenation, reductive amination, hydrogenation
C4-[(S,S)-teth-TrisDPEN RuCl]
Product number: C1-368
CAS number: 1630736-02-5
Mol weight: 746.4
Reaction type: transfer hydrogenation, reductive amination, hydrogenation

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