NR-36
Product number: NR-36
Johnson Matthey’s nitroreductase (NR) has been selected for its excellent activity with a wide selection of substrates and to accommodate various synthetic needs of our customers. Substrates accepted by the NR enzyme include aromatic and heteroaromatic nitro compounds[1].
A notable feature of this catalytic system is the exquisite chemoselectivity. Substrates containing halogens or other functional groups that could be lost or reduced during chemical nitroreduction (i.e. O-benzyl, C-C double bonds, nitriles) are redyced by the nitroreductase vanadium catalytic system only at the moiety, leaving the other fuctional groups untouched.
(1) Synergistic nitroreductase/vanadium catalysis enables chemoselective nitro reductions to anilines in the absence of hydrogen gas. Curr. Res. Chem Biol. 2022, 2, 100026