ADH-150

Catalogue Number: ADH-150

An alcohol dehydrogenase (ADH) for the reduction of ketones and aldehydes to the corresponding alcohols. Enantiopure alcohols can be obtained using our ADHs.

ADHs need a cofactor (NAD+ or NADP+) for reducing the carbonyl. To be able to use this cofactor in catalytic amounts, the oxidised cofactor has to be continuously reduced, this is called cofactor regeneration. The enzymes accept either or both NAD(P)+ cofactors and their regeneration can be achieved by adding a cofactor regeneration enzyme (GDH or FDH), and its substrate (D-glucose or sodium formate, respectively).

Included in our C=O reduction kit
Chemical reaction scheme showing the reduction of a carbonyl group using ADH.

Description:
Alcohol Dehydrogenase 150

Cofactor:
NADP+ NAD+

Cofactor Regeneration:
GDH, FDH, isopropanol

Optimal pH:
6.5 - 9.5

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