Formate dehydrogenase enzyme technology
Formate dehydrogenase (FDH enzyme) oxidises formate to carbon dioxide while reducing in turn NAD+ to NADH. Carbon dioxide leaves the reaction media as a gaseous molecule, favouring NADH cofactor regeneration. FDH enzymes can be engineered to achieve the optimal activity and selectivity of your application.
Advantages of using formate dehydrogenase:
- An FDH enzyme has unique characteristics for biocatalytic applications because no residual side products are left in the reaction as carbon dioxide evaporates, unlike other enzymes such as GDH.
