GDH-5: Glucose dehydrogenase enzyme | Johnson Matthey
GDH-5
Catalogue Number: GDH-5
Glucose dehydrogenase (GDH) catalyses the oxidation of D-glucose to D-glucolactone, while reducing in turn NAD+ or NADP+ to NADH and NADPH, respectively. The product of this reaction, D-glucolatone, spontaneously and irreversibly hydrolyses in water to gluconic acid, hence favouring the formation of reduced NADH and NADPH.
GDH-5 accepts both NAD+ and NADP+ however it has a remarkable activity with NADP+, making an interesting alternative to GDH-101 if the enzyme of choice prefers NADP + as cofactor