Alanine dehydrogenase enzyme technology

Alanine dehydrogenase (AlaDH enzyme) catalyses the reductive amination of pyruvate to L-alanine. AlaDH enzymes requires NADH cofactor and ammonia to carry out the reaction.  NAD+ is regenerated to NADH by GDH. 
 

Advantages of using alanine dehydrogenase:

  • Regenerates alanine directly, creating a closed-loop system that efficiently recycles the amino donor.
  • AlaDH enzymes avoid by-product accumulation, potentially simplifying downstream processing.

AlaDH enzyme product

AlaDH-6
Enzyme class number: 1.4
Optimal pH: 6.0-9.0
Reaction type: Reductive amination

Get in touch

Send us a message to request a quote or ask our advice. We'd be happy to hear from you.