HTE catalyst screening plates

Accelerating your lab productivity

Johnson Matthey's catalyst screening plates are a ready-to-use, 96 well solution for rapid hit identification in cross-coupling applications. Designed for seamless integration into high-throughput experimentation (HTE) workflows, the plates contain 24 unique catalysts selected by our team of experts. The screening plates utilise chemical-coated glass beads (ChemBeads)1 with a standard catalyst loading of 1 umol per well. Plates are also available with catalyst loadings from 20 nmol to 20 umol.

Improve your workflow productivity

Dry catalyst loading minimises composition change, providing more accurate hit identification.
Designed to work directly with existing HTE screening equipment.
Reduces plate design and preparation time with a fast, economical alternative.

Catalyst and ligand diversity

Available formats

C-C and C-N cross-coupling reactions 

24 unique catalysts
π-allyl palladium technology, Buchwald Pd G3 precatalysts, PdL2X2 precatalysts, Pd precursors
Diverse phosphine ligands
Covering a wide spectrum of the reaction space

High-throughput screening kit contents

Product number Description C-C plate C-N plate
Pd-62 PdCl2(MeCN)2 + +
Pd-93 Pd(dba)2 +
Pd-94 Pd2(dba)3 + +
Pd-100 PdCl2(PPh3)2 +
Pd-110 [Pd(allyl)Cl]2 + +
Pd-111 Pd(OAc)2 + +
Pd-117 PdCl2(DPEPhos) +
Pd-122 PdCl2[P(tBu)2(Ph)]2 +
Pd-123S PdCl2(S)-BINAP +
Pd-126 PdCl2(dppp) +
Pd-132 PdCl2(AmPhos)2 +
Pd-161 AmPhos Pd(crotyl)Cl + +
Pd-162 P(tBu)3 Pd(crotyl)Cl + +
Pd-166 PdCl2[P(tBu) (Cy)2]2 +
Pd-170 XPhos Pd(crotyl)Cl + +
Pd-171 RuPhos Pd(crotyl)Cl + +
Pd-172 SPhos Pd(crotyl)Cl + +
Pd-173 [BrettPhos Pd(allyl)]OTf + +
Product number Description C-C plate C-N plate
Pd-174 [tBuXPhos Pd(allyl)]OTf + +
Pd-175 [tBuBrettPhos Pd(allyl)]OTf +
Pd-177 XantPhos Pd(allyl)Cl + +
Pd-178 PCy3 Pd(crotyl)Cl +
Pd-181 P(o-tolyl)3 Pd(crotyl)Cl +
Pd-188 CyJohnPhos Pd(crotyl)Cl +
Pd-209 tBuXPhos Pd G6 +
Pd-210 tBuBrettPhos Pd G6 +
Pd-215 [RockPhos Pd(allyl)]OTf +
Pd-216 [Me3OMettBuXPhos Pd(allyl)]OTf +
Pd-217 CPhos Pd(crotyl) Cl +
Pd-218 [EPhos Pd(allyl)]OTf +
Pd-219 [GPhos Pd(allyl)]OTf +
Pd-220 [AlPhos Pd(allyl)OTf +
Pd-221 [MorDalPhos Pd(crotyl)OTf +
BPC-307 P(Ad)2(nBu) Pd G3 + +
Ni-132 Ni(PPh3)2(1-naphthyl)Cl +

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Additional resources

HTE catalyst screening plate user guide

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HTE catalyst screening plate layout

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1. Tu, N.P.; Wang, T. RSC Med. Chem. 2026, 17, 52-62.